Photo by Cindy Keese

Search Holiday Homes in Seneca

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Browse Select Seneca Holiday Homes

LAKEFRONT Retreat! <br>Escape To Lake Hartwell in this lakeside cottage!
10.0 out of 10, Exceptional, (34)
"Extremely clean, great location. Quiet, relaxing time at the lake."
LAKEFRONT Retreat! <br>Escape To Lake Hartwell in this lakeside cottage!
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
9.6 out of 10, Exceptional, (5)
"Home was just as described online and host was very prompt to respond with answers to questions. We all loved the back yard as it was very peaceful and had plenty of room for the pups to run and play."
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
10.0 out of 10, Exceptional, (1)
"Nice, private and clean accommodations to visit the Seneca area… would definitely stay again!!"
The price is 2 268 kr
includes taxes & fees
30 Jun - 1 Jul
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
9.8 out of 10, Exceptional, (133)
"Overall, good stay. Dock had only one light working."
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
Salem Vacation Rental w/ Lake Keowee Access!
10.0 out of 10, Exceptional, (1)
Salem Vacation Rental w/ Lake Keowee Access!
Lake Hartwell - House w/dock, screened in porch and firepit
9.8 out of 10, Exceptional, (32)
"We spent a wonderful Father's Day weekend at the lake with our family and grandparents. The house is situated on a very nice and quiet cove, which made it perfect for swimming. The huge screened in porch was such a nice feature, and the hot tub was fun for us all as well. We will definitely be back!"
Lake Hartwell - House w/dock, screened in porch and firepit
Super Regional Special!LARGE Lake House. Close to Clemson-Family Friendly.
9.4 out of 10, Exceptional, (40)
"Lake house was lovely! Very cozy cabin tucked away from the hustle and bustle of Clemson. Perfect for our family and friends."
Super Regional Special!LARGE Lake House. Close to Clemson-Family Friendly.
Well Appointed Bungalow on Beautiful Horse Farm w/boat parking, close to Clemson
10.0 out of 10, Exceptional, (57)
"This great place was just what we needed for a busy weekend in Clemson. Only about 20 minutes from campus, it was nice to deviate from a the hotel norm."
Well Appointed Bungalow on Beautiful Horse Farm w/boat parking, close to Clemson
Lake Hartwell Home w/ Dock < 10 Miles to Clemson!
9.8 out of 10, Exceptional, (49)
"We went to see our son in law graduate with his masters degree. It was the perfect location to get to Clemson and far enough to enjoy the beautiful lake. It’s only 10 minutes from Clemson. 😜 we would definitely stay here again and maybe rent a boat next time."
Lake Hartwell Home w/ Dock < 10 Miles to Clemson!
Skipping rocks and soaking it all in at this gorgeous lake retreat.
10.0 out of 10, Exceptional, (1)
"We enjoyed our stay. Great views and nice house. The dock view is amazing!"
Skipping rocks and soaking it all in at this gorgeous lake retreat.
Lake Keowee Retreat with boat slip & lots of entertainment space near Clemson U
10.0 out of 10, Exceptional, (83)
"We spent 5 days here with our adult children and had a great time. The chalet is very clean and comfortable and host was easy to reach and responsive to questions. Easy walk down to shared dock and pretty quick to get anywhere on lake with boat. Lovely sunsets on the dock!"
The price is 7 562 kr
includes taxes & fees
26 Jun - 27 Jun
Lake Keowee Retreat with boat slip & lots of entertainment space near Clemson U
2-209C - Coopers Cozy Cabin * Lake Hartwell * WIFI * Pets Welcome
9.6 out of 10, Exceptional, (57)
"Rented the house to look at properties to buy. The home was perfect and I enjoyed some me time on the dock to reflect about my decision to move to this area."
2-209C - Coopers Cozy Cabin * Lake Hartwell * WIFI * Pets Welcome
Cozy Remodeled Lake Hartwell Home in a quiet cove.
10.0 out of 10, Exceptional, (21)
"We enjoyed our stay so very much. The house was perfect for us. Good memories were made. Thank you for sharing your happy place! Thank you for being a blessing!"
Cozy Remodeled Lake Hartwell Home in a quiet cove.
Quiet Lake House 5 Min from Clemson University
9.8 out of 10, Exceptional, (7)
"Great location to Baseball/softball fields and very little traffic on that side of town. The listing had hot tub on the amenities but there is not one. It definitely has the feel of a rental and not someone’s weekend home. Very Clean! Lots of usable space. Overall it was a great place."
Quiet Lake House 5 Min from Clemson University
OUTER BANKS
8.0 out of 10, Very good, (8)
"We brought a few of our teens from our youth group for a winter retreat, every one of them said that it was a beautiful house with so much to do. It also made a great laser tag arena."
OUTER BANKS
New! Lakefront with Views from Every Window - With Dock, Fire Pit, BBQ, Kayaks
10.0 out of 10, Exceptional, (43)
"Everything was fantastic! Beautiful home and property. Francie was so helpful and great to work with. Highly recommend this property and would love to come back."
New! Lakefront with Views from Every Window - With Dock, Fire Pit, BBQ, Kayaks
Boutique hotel in historic downtown Seneca. Room #4, King bed.
9.6 out of 10, Exceptional, (4)
"We enjoyed spending 2 nights at this quaint spot! The Host was very easy to talk to. We would definitely stay here again."
The price is 2 254 kr
includes taxes & fees
26 Jun - 27 Jun
Boutique hotel in historic downtown Seneca. Room #4, King bed.
Charming 4 bedroom/2bath Lakefront home convenient to Marina and Clemson!
10.0 out of 10, Exceptional, (14)
"We really enjoyed Doc’s house. It was perfect. We had two families and we had plenty of room. We would highly recommend this house. We also enjoyed the screen porch. The house has got everything you need from the basic necessities to the swimming rafts, noddles extra chairs, firepit. We loved swimming off the dock, it was very deep. We parked our boat under the covered dock area during the afternoon storms. We would definitely stay at Docs place again when we comeback to Lake Keowee. Thank you...
Charming 4 bedroom/2bath Lakefront home convenient to Marina and Clemson!
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!
10.0 out of 10, Exceptional, (71)
"This house was absolutely wonderful! There were plenty of beds and plenty of room for our entire family and a few friends. The location was great, the sunsets and sunrises were beautiful, and it was so quiet the entire time. I think our favorite spot was the screened in sunroom. It was especially nice to have the house stocked with paper products and most of the things anyone would need in the kitchen. The only negative thing I can say is that the house needed a little TLC on the outside. The...
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!
S. Circle - Beautifully Restored Home
9.0 out of 10, Wonderful, (18)
"Loved the home! "
S. Circle - Beautifully Restored Home
Don't see what you're looking for?
See all available properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in Seneca

Incredible 10 BR home with pool and hot tub
8.0 out of 10, Very good, (1)
"Close to Seneca and Clemson University. Go Tigers!! This house is very spacious and well appointed for large groups of people. It is still early in the season so they were not quite ready for us. The pool, hot tub, wi-fi, televisions were not operational. There was no communicaiton sent to us about any of these none working items. Without notice, a tech was sent to the property (our first morning) to attempt to get the Wi-Fi up and running, however, the passwords are with the home owner...
Incredible 10 BR home with pool and hot tub
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
10.0 out of 10, Exceptional, (68)
"We rented this for my daughter’s wedding and we couldn’t have picked a better place! The house & yard is absolutely gorgeous and the house is completely stocked with everything you would need to cater to a large family staying there. Our family thoroughly enjoyed their stay. Communication was also a 10 and I really appreciated that!"
The price is 21 116 kr
includes taxes & fees
14 Jul - 15 Jul
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
June Discounted Rates! Waterfront Home w/ Covered Dock, 2 Decks, & Pet Friendly
9.8 out of 10, Exceptional, (315)
"We had a great time and the owners were fantastic. They texted us several times to make sure everything was going well. The neighbors were very friendly. I would highly recommend this home for your vacation spot on Lake Keowee."
June Discounted Rates! Waterfront Home w/ Covered Dock, 2 Decks, & Pet Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Seneca Holiday Homes information

Number of reviews
Accommodation
Holiday Homes
Lowest Price
Highest Price

Seneca Hotel Reviews
Expedia verified reviews