- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 45% on select hotels after you book a flight*
Plan, book, fly with confidence
More to explore for Santiago de Cuba
Heading to Santiago de Cuba? Explore Santiago de Cuba with Expedia's Travel Guides to find the best hotels, holiday packages, car hire deals and more!
Top Flight Destinations In World
*Available to Expedia members.